Biomolecules and nanostructures
The Optical Sciences group studies the interaction of light and matter. Our current focus is on detection and sensing/imaging with an emphasis on the development of integrated photonics. We are part of Twente University's Department of Science and Technology and member of the MESA+ institute.
AN ATOMIC-FORCE MICROSCOPIC STUDY OF THE SYNAPTONEMAL COMPLEX
PUTMAN CAJ, DIETRICH AJJ, DEGROOTH BG, VANMARLE J, HEYTING C, VANHULST NF, GREVE J
vol 24 issue 3: p273-p277 1993
The chromosomal structure which is specific for meiosis, the synaptonemal complex (SC), plays a major role in chromosome pairing and the recombination of genetic material. The SC was studied using atomic force microscopy (AFM). The results of this study confirm the results of light and electron microscopic studies of the SC. The SC primarily shows a tripartite structure, composed of two lateral elements and a central element connected to each other by transversal elements. The lateral element of the SC shows a lateral subdivision in secondary lateral strands. In addition, a new repetitive transversal subdivision of the lateral elements was observed. Furthermore, the SC substructure which is probably responsible for recombination, the recombination nodule, could be observed ouside the confines of the SC.