Optical Sciences

Biomolecules and nanostructures

The Optical Sciences group studies the interaction of light and matter. Our current focus is on detection and sensing/imaging with an emphasis on the development of integrated photonics. We are part of Twente University's Department of Science and Technology and member of the MESA+ institute.

 

DNA-Based Molecular Wires: Multiple Emission Pathways of Individual Constructs

(full pdf)

Gabriel Sánchez-Mosteiro, Erik M. H. P. van Dijk, Jordi Hernando, Mike Heilemann, Philip Tinnefeld, Markus Sauer, Felix Koberlin, Matthias Patting, Michael Wahl, Rainer Erdmann, Niek F. van Hulst, and Mariá F. García-Parajó
J. Phys. Chem. B
vol. 101 10.1021 p26349-26353 dec 05 2006

The extent of photon energy transfer through individual DNA-based molecular wires composed of five dyes is investigated at the single molecular level. Combining single-molecule spectroscopy and pulse interleaved excitation imaging, we have directly resolved the time evolution spectral response of individual constructs, while simultaneously probing DNA integrity. Our data clearly show that intact wires exhibit photon-transfer efficiencies close to 100% across five dyes. Dynamical and multiple pathways for the photon emission resulting from conformational freedom of the wire are readily uncovered. These results provide the basis for guiding the synthesis of DNA-based supramolecular arrays with improved photon transport at the nanometer scale.
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