Optical Sciences

Biomolecules and nanostructures

The Optical Sciences group studies the interaction of light and matter. Our current focus is on detection and sensing/imaging with an emphasis on the development of integrated photonics. We are part of Twente University's Department of Science and Technology and member of the MESA+ institute.

 

Rapid identification of heterogeneous mixture components with hyperspectral coherent anti- Stokes Raman scattering imaging

(full pdf)

Erik T. Garbacik, Jennifer L. Herek, Cees Otto and Herman L. Offerhaus
Journal of Raman Spectroscopy
may 3, 2012
doi:10.1002/jrs.4064

For the rapid analysis of complicated heterogeneous mixtures, we have developed a method to acquire and intuitively display hyperspectral coherent anti-Stokes Raman scattering (CARS) images. The imaging is performed with a conventional optical setup based around an optical parametric oscillator. Color coding each frame of the resulting hyperspectral data cube according to vibrational frequency results in a two-dimensional projection wherein each compound appears with a unique hue. We demonstrate the capabilities of this systemby recording a hyperspectral CARS data stack of a heterogeneousmixture composed of seven crystalline amino acids and subsequently identifying each of themby direct visual analysis of the colored projection. © 2012 John Wiley & Sons, Ltd.
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