Biomolecules and nanostructures
The Optical Sciences group studies the interaction of light and matter. Our current focus is on detection and sensing/imaging with an emphasis on the development of integrated photonics. We are part of Twente University's Department of Science and Technology and member of the MESA+ institute.
Rapid identification of heterogeneous mixture components with hyperspectral coherent anti- Stokes Raman scattering imaging(full pdf)
Erik T. Garbacik, Jennifer L. Herek, Cees Otto and Herman L. Offerhaus
Journal of Raman Spectroscopy
may 3, 2012
For the rapid analysis of complicated heterogeneous mixtures, we have developed a method to acquire and intuitively display hyperspectral coherent anti-Stokes Raman scattering (CARS) images. The imaging is performed with a conventional optical setup based around an optical parametric oscillator. Color coding each frame of the resulting hyperspectral data cube according to vibrational frequency results in a two-dimensional projection wherein each compound appears with a unique hue. We demonstrate the capabilities of this systemby recording a hyperspectral CARS data stack of a heterogeneousmixture composed of seven crystalline amino acids and subsequently identifying each of themby direct visual analysis of the colored projection. © 2012 John Wiley & Sons, Ltd.