Biomolecules and nanostructures
The Optical Sciences group studies the interaction of light and matter. Our current focus is on detection and sensing/imaging with an emphasis on the development of integrated photonics. We are part of Twente University's Department of Science and Technology and member of the MESA+ institute.
Near-field fluorescence imaging with 32 nm resolution based on microfabricated cantilevered probes(full pdf)
Eckert R, Freyland JM, Gersen H, Heinzelmann H, Schurmann G, Noell W, Staufer U, de Rooij NF
APPLIED PHYSICS LETTERS
vol 77 issue 23: p3695-p3697 DEC 4 2000
High-resolution near-field optical imaging with microfabricated probes is demonstrated. The probes are made from solid quartz tips fabricated at the end of silicon cantilevers and covered with a 60-nm-thick aluminum film. Transmission electron micrographs indicate a continuous aluminum layer at the tip apex. A specially designed instrument combines the advantages of near-field optical and beam-deflection force microscopy. Near-field optical data of latex bead projection patterns in transmission and of single fluorophores have been obtained in constant-height imaging mode. An artifact-free optical resolution of 31.7 +/-3.6 nm has been deduced from full width at half maximum values of single molecule images. (C) 2000 American Institute of Physics. [S0003-6951(00)05449-8].