Biomolecules and nanostructures

The Optical Sciences group studies the interaction of light and matter at the nanoscale. We do this by exploring ways to shape light and its environment. It's what we call active and passive control. Our current focus is on the interaction of light with biomolecules and nanostructures. We are part of Twente University's Department of Science and Technology and member of the MESA+ institute.
We participate in the EU-COST actions MP1102: Coherent Raman microscopy (MicroCor) and CM1202: Supramolecular photocatalytic water splitting (PERSPECT-H2O)

Articles

Refereed articles by the Optical Sciences group

Excited-State Proton-Transfer Processes of DHICA Resolved: From Sub-Picoseconds to Nanoseconds

In planta imaging of Δ⁹-tetrahydrocannabinolic acid in Cannabis sativa L. with hyperspectral coherent anti-Stokes Raman scattering microscopy

Stimulated-emission pumping enabling sub-diffraction-limited spatial resolution in coherent anti-Stokes Raman scattering microscopy

Probing the origin of fluorescence quenching of a graphene-porphyrin hybrid material

Hyperspectral coherent anti-Stokes Raman scattering microscopy for in situ analysis of solid-state crystal polymorphs

Active and Passive Control of Zinc Phthalocyanine Photodynamics

25 kHz narrow spectral bandwidth of a wavelength tunable diode laser with a short waveguide-based external cavity

Measurement of a band-edge tail in the density of states of a photonic-crystal waveguide

Bottom-Up Approach to Eumelanin Photoprotection: Emission Dynamics in Parallel Sets of Water-Soluble 5,6-Dihydroxyindole- Based Model Systems

Polyglutamine Aggregate Structure In Vitro and In Vivo; New Avenues for Coherent Anti-Stokes Raman Scattering Microscopy

Rapid identification of heterogeneous mixture components with hyperspectral coherent anti- Stokes Raman scattering imaging

Phase aspects of (broadband) stimulated Raman scattering

Extraction of optical Bloch modes in a photonic-crystal waveguide

Background-free nonlinear microspectroscopy with vibrational molecular interferometry

Computational optimization of phase shaped CARS

Photophysics of indole-2-carboxylic acid in an aqueous environment studied by fluorescence spectroscopy in combination with ab initio calculations

Background-Free Nonlinear Microspectroscopy with Vibrational Molecular Interferometry

Intraoperative Near-Infrared Fluorescence Tumor Imaging with Vascular Endothelial Growth Factor and Human Epidermal Growth Factor Receptor 2 Targeting Antibodies

Pharmaceutical applications of non-linear imaging

Inverse-Woodpile Photonic Band Gap Crystals with a Cubic Diamond-like Structure Made from Single-Crystalline Silicon

Controlling the quality factor of a tuning-fork resonance between 9 and 300 K for scanning-probe microscopy

Coherent control of vibrational transitions: Discriminating molecules in mixtures

Vibration transfers to measure the performance of vibration isolated platforms on site using background noise excitation

Influence of the length and grafting density of PNIPAM chains on the colloidal and optical properties of quantum dot/PNIPAM assemblies

A theoretical investigation of super-resolution CARS imaging via coherent and incoherent saturation of transitions

Implementation of vibrational phase contrast coherent anti-Stokes Raman scattering microscopy

Phase-shaping strategies for coherent anti-Stokes Raman scattering

Enhanced surface plasmon polariton propagation length using a buried metal grating

Investigation of adaptive laser pulse shaping by direct estimation of group delay profile

Imaging of surface plasmon polariton interference using phase-sensitive photon scanning tunneling microscope

Modeling of mode locking in a laser with spatially separate gain media

Visualizing Resonances in the Complex Plane with Vibrational Phase Contrast Coherent Anti-Stokes Raman Scattering

Large scale scanning probe microscope: Making the shear-force scanning visible

Revisiting the optical properties of the FMO protein

Heterodyne interferometric polarization coherent anti-Stokes Raman scattering (HIP-CARS) spectroscopy

Exploring, tailoring, and traversing the solution landscape of a phase-shaped CARS process

Spatially dependent Rabi oscillations: An approach to sub-diffraction-limited coherent anti-Stokes Raman-scattering microscopy

Tailoring a coherent control solution landscape by linear transforms of spectral phase basis

Learning from evolutionary optimization by retracing search paths

High-resolution narrowband CARS spectroscopy in the spectral fingerprint region

Vibrational Phase Contrast Microscopy by Use of Coherent Anti-Stokes Raman Scattering

Robust orthogonal parameterization of evolution strategy for adaptive laser pulse shaping

Quantum control experiment reveals solvation-induced decoherence

Laser Induced Damage Reduction in Single-Mode Fiber Devices

Chemical Imaging of Oral Solid Dosage Forms and Changes upon Dissolution Using Coherent Anti-Stokes Raman Scattering Microscopy

Large bandwidth, highly efficient optical gratings through high index materials

Chemically selective imaging by spectral phase shaping for broadband CARS around 3000 cm−1

Carotenoid deactivation in an artificial light-harvesting complex via a vibrationally hot ground state

Spectral phase shaping for high resolution CARS

An atomic force microscope operating at hypergravity for in situ measurement of cellular mechano-response

Coherent Anti-Stokes Raman Scattering microscopy to monitor drug dissolution in different oral pharmaceutical tablets

Background free CARS imaging by phase sensitive heterodyne CARS

Nanoimprint lithography for nanophotonics in silicon

Mid-IR transmission of a large-area 2D silicon photonic crystal slab

Controlling the efficiency of an artificial light-harvesting complex

Application of spectral phase shaping to high resolution CARS spectroscopy

Fabrication of three-dimensional nanostructures by focused ion beam milling

Characterizing the functional dynamics of zinc phthalocyanine from femtoseconds to nanoseconds

73-nm tuning of a double-clad Yb3+-doped fiber laser based on a hybrid array

Optical antennas direct single-molecule emission (featuring cover story)

Ultrafast energy transfer dynamics of a bioinspired dyad molecule

Nanometer-scale organization of the alpha subunits of the receptors for IL2 and IL15 in human T lymphoma cells

Near-field observation of spatial phase shifts associated with Goos-Hänschen and Surface Plasmon Resonance effects

Reversible Polarization Control of Single Photon Emission

Novel instrument for surface plasmon polariton tracking in space and time

Ultrafast single-molecule photonics: Excited state dynamics in coherently coupled complexes

Holographic injection locking of a broad area laser diode via a photorefractive thin-film device

Shot noise limited heterodyne detection of CARS signals

A Monopole Antenna at Optical Frequencies: Single-Molecule Near-Field Measurements

Spectral investigation of a large-area 2D silicon photonic crystal slab for mid-IR radiation

Near-field driving of a optical monopole antenna

Nanoscale Organization of the Pathogen Receptor DC-SIGN Mapped by Single-Molecule High-Resolution Fluorescence Microscopy

Photonics - Light in chains

Wide wavelength-tuning of a double-clad Yb³⁺-doped fiber laser based on a fiber Bragg grating array

Ultrafast evolution of photonic eigenstates in k-space

Low-noise rotating sample holder for ultrafast transient spectroscopy at cryogenic temperatures

Power-Law Blinking in the Fluorescence of Single Organic Molecules

λ/4 Resonance of an Optical Monopole Antenna Probed by Single Molecule Fluorescence

Noncritical phase-matched lithium triborate optical parametric oscillator for high resolution coherent anti-Stokes Raman scattering spectroscopy and microscopy

DNA-Based Molecular Wires: Multiple Emission Pathways of Individual Constructs

Accurate and unbiased estimation of power-law exponents from single-emitter blinking data

Effect of Disorder on Ultrafast Exciton Dynamics Probed by Single Molecule Spectroscopy

Strong Modification of the Nonlinear Optical Response of Metallic Subwavelength Hole Arrays

Single light emitters in electrospun polymer nanofibers: Effect of local confinement on radiative decay

Synthesis and Characterization of Long Perylenediimide Polymer Fibers: From Bulk to the Single-Molecule Level

The effect of higher-order dispersion on slow light propagation in photonic crystal waveguides

Excitation of surface plasmons at a SiO2 /Ag interface by silicon quantum dots:
Experiment and theory

Compact high-resolution spectral phase shaper

Creating Focused Plasmons by Noncollinear Phasematching on Functional Gratings

Power-Law-Distributed Dark States are the Main Pathway for Photobleaching of Single Organic Molecules

Beaded Electrospun Fibers for Photonic Applications

Role of shape and localized resonances in extraordinary transmission through periodic arrays of subwavelength holes: Experiment and theory

Near-Field Fluorescence Microscopy An Optical Nanotool to Study Protein Organization at the Cell Membrane

Local probing of Bloch mode dispersion in a photonic crystal waveguide

Single-molecule pump-probe experiments reveal variations in ultrafast energy redistribution

Energy Transfer in Single-Molecule Photonic Wires

Direct Observation of Bloch Harmonics and Negative Phase Velocity in Photonic Crystal Waveguides

How C-type lectins detect pathogens

Fluorescence lifetime fluctuations of single molecules probe local density fluctuations in disordered media: A bulk approach

Probing the negative permittivity perfect lens at optical frequencies using near-field optics and single molecule detection

Real-Space Observation of Ultraslow Light in Photonic Crystal Waveguides

Single-molecule pump-probe detection resolves ultrafast pathways in individual and coupled quantum systems

Coupling of Er ions to surface plasmons on Ag

Molecular Printboards on Silicon Oxide: Lithographic Patterning of Cyclodextrin Monolayers with Multivalent, Fluorescent Guest Molecules

Monolayer-functionalized microfluidics devices for optical sensing of acidity

Phase mapping of ultrashort pulses in bimodal photonic structures: A window on local group velocity dispersion

Single Molecule Photobleaching Probes the Exciton Wave Function in a Multichromophoric System

Influence of hole size on the extraordinary transmission through subwavelength hole arrays

Photon Antibunching Proves Emission from a Single Subunit in the Autofluorescent Protein DsRed

Near-field probing of photonic crystals

Investigation of Perylene Photonic Wires by Combined Single-Molecule Fluorescence and Atomic Force Microscopy

Near-field scanning optical microscopy in liquid for high resolution single molecule detection on dendritic cells

A Simple Approach to Sensor Discovery and Fabrication on Self-Assembled Monolayers on Glass

Propagation of a femtosecond pulse in a microresonator visualized in time

Strong Influence of Hole Shape on Extraordinary Transmission through Periodic Arrays

Multistep Energy Transfer in Single Molecular Photonic Wires

Large-area two-dimensional silicon photonic crystals for infrared light fabricated with laser interference lithography

Segment Dynamics in Thin Polystyrene Films Probed by Single-Molecule Optics

Cell plasma membrane organization at nanometer scale studied with single molecule sensitive fluorescence microscopy

Single molecule near-field fluorescence microsocopy reveals hierarchical organization of C-type lectins on dendritic cells

Probing polymers with single fluorescent molecules

Effect of solvent on nanoscale polymer heterogeneity and mobility probed by single molecule lifetime fluctuations

Microdomains of the C-type lectin DC-SIGN are portals for virus entry into dendritic cells

Shear force imaging of soft samples in liquid using a diving bell concept

Tracking ultrashort pulses through dispersive media: Experiment and theory

Single molecule lifetime fluctuations reveal segmental dynamics in polymers

Near-field optical investigation of three-dimensional photonic crystals

Amplitude and phase evolution of optical fields inside periodic photonic stuctures

Molecular fluorescence lifetime fluctuations: on the possible role of conformational effects

Photoplastic near-field optical probe with sub-100 nm aperture made by replication from a nanomould

Excitonic behavior of rhodamine dimers: A single-molecule study

Film thickness effects on single molecule optical probing of polymers

Single molecule probing of polymers and supramolecular materials

Detailed analysis of the intracavity phenomena inside a cylindrical microresonator

Single molecule studies of the red autofluorescent protein DsRed

Comment on "Local observations of phase singularities in optical fields in waveguide structures" - Reply

The nature of fluorescence emission in the red fluorescent protein DsRed, revealed by single-molecule detection

Cell biology beyond the diffraction limit: near-field scanning optical microscopy

On the role of electromagnetic boundary conditions in single molecule fluorescence lifetime studies of dyes embedded in thin films

Tracking femtosecond laser pulses in space and time

Large area photonic crystal slabs for visible light with waveguiding defect structures: Fabrication with focused ion beam assisted laser interference lithography

Visualization of mode transformation in a planar waveguide splitter by near-field optical phase imaging

Phase mapping of optical fields in integrated optical waveguide structures

Optical probing of single fluorescent molecules and proteins

Near-field effects in single molecule emission

Single molecule studies of living colors and transmembrane proteins on cells.

Single-molecule probing of nanoscale polymer dynamics.

Single molecules in the near field.

Experimental analysis of the whispering-gallery modes in a cylindrical optical microcavity

Local phase measurements of light in a one-dimensional photonic crystal

Moulded photoplastic probes for near-field optical applications

Near-field optical microscopy based on microfabricated probes

Untitled (Editorial)

Quantitative photon tunneling and shear-force microscopy of planar waveguide splitters and mixers

Looking at the photodynamics of individual fluorescent molecules and proteins

Single molecule studies of living colours.

Study of individual transmembrane proteins using a combined confocal/near field optical microscope.

Single molecule probing of nanoscale polymer dynamics

Photon scanning tunneling optical microscopy with a three- dimensional multiheight imaging mode

Influencing the angular emission of a single molecule

Near-field fluorescence imaging with 32 nm resolution based on microfabricated cantilevered probes

High-resolution photon-scanning tunneling microscope measurements of the whispering gallery modes in a cylindrical microresonator

Imaging soft samples in liquid with tuning fork based shear force microscopy

Local observations of phase singularities in optical fields in waveguide structures

Photon scanning tunneling microscopy of tailor-made photonic structures

Real-time light-driven dynamics of the fluorescence emission in single green fluorescent protein molecules

Analysis of individual (macro)molecules and proteins using near-field optics

Reconstruction of the tip-surface interaction potential by analysis of the Brownian motion of an atomic force microscope tip

Quasi interference of perpendicularly polarized guided modes observed with a photon scanning tunneling microscope

Real time light-driven dynamics of the fluorescence emission in individual green fluorescent proteins

Near-field scanning optical microscopy of single fluorescent dendritic molecules

Visualizing the whispering gallery modes in a cylindrical optical microcavity

Atomic steps with tuning-fork-based noncontact atomic force microscopy

Time-varying triplet state lifetimes of single molecules

Visualising individual green fluorescent proteins with a near field optical microscope

Single molecule mapping of the optical field distribution of probes for near-field microscopy

A physical approach to reduce nonspecific adhesion in molecular recognition atomic force microscopy

Second-order nonlinear optical properties of the four tetranitrotetrapropoxycalix[4]arene conformers

Supramolecular materials: Molecular packing of tetranitrotetrapropoxycalix[4]arene in highly stable films with second-order nonlinear optical properties

High definition aperture probes for near-field optical microscopy fabricated by focused ion beam milling

Direct visualization of dynamic protein-DNA interactions with a dedicated atomic force microscope

NFO-4 - Selected papers from the 4th International Conference on Near-Field Optics and Related Techniques - Jerusalem, Israel, 9-13 February 1997 - Foreword

Near-field optical and shear-force microscopy of single fluorophores and DNA molecules

Tuning fork shear-force feedback

Near-field optical microscopy for DNA studies at the single molecular level

Chromatin structure in bands and interbands of polytene chromosomes imaged by Atomic Force Microscopy

Single molecule rotational and translational diffusion observed by near-field scanning optical microscopy

Height anomalies in tapping mode atomic force microscopy in air caused by adhesion

Dynamic behavior of tuning fork shear-force feedback

Second-order nonlinear optical active calix[4]arene polyimides suitable for frequency doubling in the UV region

Near-field fluorescence imaging of genetic material: Toward the molecular limit

Molecular and macroscopic second order nonlinear optical properties of calix[4]arenes

Time-resolved hyper-Rayleigh scattering: Measuring first hyperpolarizabilities beta of fluorescent molecules

Fluorescence in situ hybridization on human metaphase chromosomes detected by near-field scanning optical microscopy

Microfabrication of near-field optical probes

Study of the leakage field of magnetic force microscopy thin- film tips using electron holography

Noncritically phase-matched second harmonic generation of blue light in Si[O]N-calix[4]arene slab type waveguides

Biological application of near-field optical microscopy

Towards molecular resolution

Cerenkov-type second-harmonic generation in thin planar calix[4]arene waveguiding films

Detection of fluorescence in situ hybridization on human metaphase chromosomes by near-field scanning optical microscopy

Multi-detection and polarisation contrast in scanning near- field optical microscopy in reflection

Development of an integrated NSOM probe

NFO-3 - Selected papers from the 3rd international conference on near-field optics and related techniques - Brno, Czech Republic, 9-11 May 1995 - Topical Meeting European Optical Society (EOS) - Foreword

POLARIZATION CONTRAST IN PHOTON SCANNING-TUNNELING-MICROSCOPY COMBINED WITH ATOMIC-FORCE MICROSCOPY

POLARIZATION CONTRAST IN FLUORESCENCE SCANNING NEAR-FIELD OPTICAL REFLECTION MICROSCOPY

DIELECTRIC AND FLUORESCENT SAMPLES IMAGED BY SCANNING NEAR- FIELD OPTICAL MICROSCOPY IN REFLECTION

FLUORESCENCE IN-SITU HYBRIDIZATION ON HUMAN METAPHASE CHROMOSOMES DETECTED BY NEAR-FIELD MICROSCOPY

OPTICAL CONTRAST IN NEAR-FIELD TECHNIQUES

NEAR-FIELD PLASMON AND FORCE MICROSCOPY

VISCOELASTICITY OF LIVING CELLS ALLOWS HIGH-RESOLUTION IMAGING BY TAPPING MODE ATOMIC-FORCE MICROSCOPY

POLY(DIACETYLENE) MONOLAYERS STUDIED WITH A FLUORESCENCE SCANNING NEAR-FIELD OPTICAL MICROSCOPE

TAPPING MODE ATOMIC-FORCE MICROSCOPY IN LIQUID

PHOTON SCANNING TUNNELING MICROSCOPE IN COMBINATION WITH A FORCE MICROSCOPE

ANALYSIS OF IMMUNOLABELED CELLS BY ATOMIC-FORCE MICROSCOPY, OPTICAL MICROSCOPY, AND FLOW-CYTOMETRY

HIGHLY ORDERED FILMS OF NEAT CALIX[4]ARENES FOR 2ND-ORDER NONLINEAR OPTICS

COMPACT STAND-ALONE ATOMIC-FORCE MICROSCOPE

A COMBINED NEAR-FIELD OPTICAL AND FORCE MICROSCOPE

DETERMINATION OF HYPERPOLARIZABILITY TENSOR COMPONENTS BY DEPOLARIZED HYPER RAYLEIGH-SCATTERING

NEAR-FIELD OPTICAL MICROSCOPY IN TRANSMISSION AND REFLECTION MODES IN COMBINATION WITH FORCE MICROSCOPY

COMBINED SCANNING NEAR-FIELD OPTICAL AND FORCE MICROSCOPY

NOVEL CALIXARENES IN THIN-FILMS FOR EFFICIENT 2ND-HARMONIC GENERATION

NEAR-FIELD OPTICAL MICROSCOPE USING A SILICON-NITRIDE PROBE

IMMUNOGOLD LABELS - CELL-SURFACE MARKERS IN ATOMIC FORCE MICROSCOPY

DETECTION OF INSITU HYBRIDIZATION TO HUMAN-CHROMOSOMES WITH THE ATOMIC FORCE MICROSCOPE

AN ATOMIC-FORCE MICROSCOPIC STUDY OF THE SYNAPTONEMAL COMPLEX

VACUUM CHAMBER FOR SAMPLE ATTACHMENT IN ATOMIC FORCE MICROSCOPY

NITROCALIX[4]ARENES AS MOLECULES FOR 2ND-ORDER NONLINEAR OPTICS

A DETAILED ANALYSIS OF THE OPTICAL BEAM DEFLECTION TECHNIQUE FOR USE IN ATOMIC FORCE MICROSCOPY

EVANESCENT-FIELD OPTICAL MICROSCOPY - EFFECTS OF POLARIZATION, TIP SHAPE AND RADIATIVE WAVES

ATOMIC FORCE MICROSCOPE FEATURING AN INTEGRATED OPTICAL MICROSCOPE

A THEORETICAL COMPARISON BETWEEN INTERFEROMETRIC AND OPTICAL BEAM DEFLECTION TECHNIQUE FOR THE MEASUREMENT OF CANTILEVER DISPLACEMENT IN AFM

The luminescent triplet-state of VO43-In Ypo4 .1.Polarization of the emission

CHIRAL PYRROLO[1,2-A]QUINOLINES AS 2ND-ORDER NONLINEAR OPTICAL- MATERIALS

Atomic force microscope with integrated optical microscope for biological applications

HIGH-RESOLUTION IMAGING OF DIELECTRIC SURFACES WITH AN EVANESCENT FIELD OPTICAL MICROSCOPE

An Evanescent-Field Optical Microscope